You can run same test case with different test data very smoothly by just writing some utility functions either in vb script or in java or any language you are comfortable with. Automation testing is the best way to do this kind of testing. If you trying web service testing you can simply install this free app in your mobile and test with various test data. Link -Download and install in mobile Web Service Testing tool:https://play.google.com/store/apps/details?id=rester.restapitester