A quick Google shows plenty of people doing this, including This page from WatirMelon ( if you dont know of this site could be worth your while reading it, lots of good stuff on it )
and an example of using ci_reporter is here
In theory you could configure Jenkins to send emails (see this too) to an email address that bugzilla is monitoring to create/update bugs.
Alternatively, a Jenkins notifier could be configured to create a bugzilla ticket via xmlrpc (I don't know of an existing jenkins plugin that does this, however.)
I am running Watir scripts from Jenkins CI on a couple of projects. I do plan to write about it at my blog soon. If you have specific questions, please ask. I have recently recorded a screencast about the entire test automation solution I have developed for a client: Test automation at HomeSwap.com